Cancer Res 1994;54:2390-2397. Antimicrob Agents Chemother 1986;30(3):499-501. Some early research suggests that taking a specific garlic product for 12 months reduces the risk of sudden death and heart attack in people at risk for developing clogged arteries. A., Connock, M. J., and Maslin, D. J. JAMA 1-3-2001;285(1):41-42. View abstract. Wang BH, Zuzel KA, Rahman K, Billington D. Treatment with aged garlic extract protects against bromobenzene toxicity to precision cut rat liver slices. Effect of raw garlic vs commercial garlic supplements on plasma lipid concentrations in adults with moderate hypercholesterolemia: a randomized clinical trial. Lopez, H. L., Ziegenfuss, T. N., Hofheins, J. E., Habowski, S. M., Arent, S. M., Weir, J. P., and Ferrando, A. Plast.Reconstr.Surg 1995;96(2):483-484. Pereira, F., Hatia, M., and Cardoso, J. Eur J Clin Res 1996;8:25-26. Bespalov, V. G., Barash, N. I., Ivanova, O. Botulism from chopped garlic: delayed recognition of a major outbreak. Dillon, S. A., Lowe, G. M., Billington, D., and Rahman, K. Dietary supplementation with aged garlic extract reduces plasma and urine concentrations of 8-iso-prostaglandin F(2 alpha) in smoking and nonsmoking men and women. Hypertension and hyperlipidaemia: garlic helps in mild cases. Contact Dermatitis 1991;25(5):330-331. Identification of the allergens: the role of mono-, di-, and trisulfides present in garlic. In vitro virucidal effects of Allium sativum (garlic) extract and compounds. The antiatherosclerotic effect of Allium sativum. Br J Pharmacol 2008;154:1691-700. Br.J Clin Pract.Suppl 1990;69:30-35. Siegers CP, Steffen B, Robke A, and et al. B., Vinjamury, S. P., Der-Martirosian, C., Kubik, E., Mishra, L. C., Shepard, N. P., Singh, V. J., Meier, M., and Madhu, S. G. Ayurvedic and collateral herbal treatments for hyperlipidemia: a systematic review of randomized controlled trials and quasi-experimental designs. Am.J Clin Nutr. View abstract. There is some scientific evidence that garlic can lower high cholesterol after a few months of treatment, but perhaps not enough to reduce heart disease. A., Andrianova, I. V., Demidova, O. N., Gorchakova, T., and Orekhov, A. N. Lipid-lowering effects of time-released garlic powder tablets in double-blinded placebo-controlled randomized study. Adachi, A. Sabitha, P., Adhikari, P. M., Shenoy, S. M., Kamath, A., John, R., Prabhu, M. V., Mohammed, S., Baliga, S., and Padmaja, U. Efficacy of garlic paste in oral candidiasis. Kasuga, S., Uda, N., Kyo, E., Ushijima, M., Morihara, N., and Itakura, Y. Pharmacologic activities of aged garlic extract in comparison with other garlic preparations. 2003;15(3):120-129. 2007;14(7-8):447-451. 2006;84(4):912-919. The effect of garlic extract on human metabolism of acetaminophen. Nutr.Res.Rev. Overall, scientific studies have provided conflicting results. Chin Med.J.(Engl.) Pediatrics 1993;91:658-9. Dausch, J. G. and Nixon, D. W. Garlic: a review of its relationship to malignant disease. An intervention study to prevent gastric cancer by micro-selenium and large dose of allitridum. Indian J Exp Biol 1982;20(7):534-536. Maleszka R, Lutomski J, Swiatlowska-Gorna B, and Rzepecka B. View abstract. Effect of purified allicin, the major ingredient of freshly crushed garlic, on cancer cell proliferation. View abstract. El Beshbishy, H. A. Aqueous garlic extract attenuates hepatitis and oxidative stress induced by galactosamine/lipoploysaccharide in rats. Brain Res. Visit the FDA MedWatch website or call 1-800-FDA-1088. Isr.Med Assoc J 2003;5(9):637-640. MedicineNet does not provide medical advice, diagnosis or treatment. 1993;106(2):93-96. An unusual garlic burn occurring on an unexpected area. View abstract. B., and Eling, T. E. Diallyl disulfide (DADS) induces the antitumorigenic NSAID-activated gene (NAG-1) by a p53-dependent mechanism in human colorectal HCT 116 cells. View abstract. Jain, R. C. Anti tubercular activity of garlic oil. View abstract. View abstract. Prostaglandins Leukot.Essent.Fatty Acids 1995;53(6):397-400. In foods and beverages, fresh garlic, garlic powder, and garlic oil are used to add flavor. Challier, B., Perarnau, J. M., and Viel, J. F. Garlic, onion and cereal fibre as protective factors for breast cancer: a French case-control study. Swanson, C. A., Mao, B. L., Li, J. Y., Lubin, J. H., Yao, S. X., Wang, J. View abstract. A placebo-controlled double-blind study. Morioka, N., Sze, L. L., Morton, D. L., and Irie, R. F. A protein fraction from aged garlic extract enhances cytotoxicity and proliferation of human lymphocytes mediated by interleukin-2 and concanavalin A. Br J Pharmacol 2008;154:1691-700. Xenobiotica 2002;32(12):1127-1138. Garlic is also used for earaches, chronic fatigue syndrome, menstrual disorders, abnormal cholesterol levels caused by HIV drugs, hepatitis, shortness of breath related to liver disease, stomach ulcers caused by H. pylori infection, exercise performance, exercise-induced muscle soreness, a condition that causes lumps in the breast tissue called fibrocystic breast disease, a skin condition called scleroderma, and lead toxicity. Wang, Q., Wang, Y., Ji, Z., Chen, X., Pan, Y., Gao, G., Gu, H., Yang, Y., Choi, B. C., and Yan, Y. Vopr.Onkol. The effects of ginkgo and garlic on warfarin use. Effect of cooking on garlic (Allium sativum l.) Antiplatelet activity and thiosulfinates content. Ekeowa-Anderson, A. L., Shergill, B., and Goldsmith, P. Allergic contact cheilitis to garlic. View abstract. Durak, I., Kavutcu, M., Aytac, B., Avci, A., Devrim, E., Ozbek, H., and Ozturk, H. S. Effects of garlic extract consumption on blood lipid and oxidant/antioxidant parameters in humans with high blood cholesterol. Early research shows that applying ointment containing raw garlic to a wound after surgery improves healing more than applying ointment without garlic. Ledezma E, Marcano K, Jorquera A. Efficacy of ajoene in the treatment of tinea pedis: A double-blind and comparative study with terbinafine. Garlic might increase how quickly the body breaks down saquinavir. This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. View abstract. J Nutrit 1982;112(2):241-248. J Nutr. It is also applied to the skin for hair loss and thrush. Garlic is used for many conditions related to the heart and blood system. View abstract. View abstract. J Altern.Complement Med 2007;13(1):83-95. J.Burn Care Res. Fortschr.Med 12-20-1990;108(36):703-706. Chest pain (angina). View abstract. 2007;73(1):29-32. Tu, H. K., Pan, K. F., Zhang, Y., Li, W. Q., Zhang, L., Ma, J. L., Li, J. Y., and You, W. C. Manganese superoxide dismutase polymorphism and risk of gastric lesions, and its effects on chemoprevention in a Chinese population. Effect of aged garlic extract against methotrexate-induced damage to the small intestine in rats. Effect of garlic on lipid profile and psychopathologic parameters in people with mild to moderate hypercholesterolemia. Am J Gastroenterol 1999;94:1200-2. A pilot study to determine the effectiveness of garlic oil capsules in the treatment of dyspeptic patients with Helicobacter pylori. Kenzelmann R, Kade F. Limitation of the deterioration of lipid parameters by a standardized garlic-ginkgo combination product. View abstract. View abstract. Arch Oral Biol. View abstract. Ann Allergy Asthma Immunol 2013;111(1):64-5. View abstract. Ruocco, V., Brenner, S., and Lombardi, M. L. A case of diet-related pemphigus. Controlled double-blind study of subjects with reduced HDL2-cholesterol]. View abstract. View abstract. Effects of garlic powder tablets on patients with hyperlipdaemia in Canadian clinical practice. View abstract. View abstract. View abstract. Ekeowa-Anderson, A. L., Shergill, B., and Goldsmith, P. Allergic contact cheilitis to garlic. Allium vegetables and risk of prostate cancer: a population-based study. Ried K, Toben C, Fakler P. Effect of garlic on serum lipids: an updated meta-analysis. View abstract. View abstract. Sasaki J, Kita T, Ishita K, et al. 9-26-2003;73(19):2515-2526. Cancer of the esophagus. 1999;129(2):336-342. J Nutr. Lancet 1999;354:353-4. View abstract. Contact Dermatitis 1992;27(5):333-334. Gallwitz, H., Bonse, S., Martinez-Cruz, A., Schlichting, I., Schumacher, K., and Krauth-Siegel, R. L. Ajoene is an inhibitor and subversive substrate of human glutathione reductase and Trypanosoma cruzi trypanothione reductase: crystallographic, kinetic, and spectroscopic studies. Athlete's foot (Tinea pedis). Farrell, A. M. and Staughton, R. C. Garlic burns mimicking herpes zoster. Garlic (Allium sativum) for disease prevention. [Garlic and coronary heart disease. Wang, Y., Zhang, L., Moslehi, R., Ma, J., Pan, K., Zhou, T., Liu, W., Brown, L. M., Hu, Y., Pee, D., Gail, M. H., and You, W. Long-term garlic or micronutrient supplementation, but not anti-Helicobacter pylori therapy, increases serum folate or glutathione without affecting serum vitamin B-12 or homocysteine in a rural Chinese population. Antiviral constituents from Allium sativum. Contact Dermatitis 1980;6(5):356-357. 2006;45(10):1161-1163. There have been reports of bleeding after surgery in people who have taken garlic. View abstract. View abstract. View abstract. Khoo YS, Aziz Z. Garlic supplementation and serum cholesterol: a meta-analysis. View abstract. Suppression of LDL oxidation by garlic. Medications that might be affected include certain heart medications called calcium channel blockers (diltiazem, nicardipine, verapamil), cancer drugs (etoposide, paclitaxel, vinblastine, vincristine, vindesine), fungus-fighting drugs (ketoconazole, itraconazole), glucocorticoids, alfentanil (Alfenta), cisapride (Propulsid), fentanyl (Sublimaze), lidocaine (Xylocaine), losartan (Cozaar), midazolam (Versed), and others. Zhang XH, Lowe D, Giles P, et al. J Nutr 2001;131:1118S-9S.. View abstract. 1998;84(2):213-215. Carcinogenesis 1996;17:477-84. Cytochrome P450 phenotypic ratios for predicting herb-drug interactions in humans. Protective role of natural antioxidant supplementation on testicular tissue after testicular torsion and detorsion. View abstract. Am J Gastroenterol 2000;95:820-1. Mol Nutr Food Res 2007;51(11):1386-97. View abstract. Another important factor in deciding the top ten was cost. Garlic might increase how quickly the body breaks down cyclosporine (Neoral, Sandimmune). Hu, J., Nyren, O., Wolk, A., Bergstrom, R., Yuen, J., Adami, H. O., Guo, L., Li, H., Huang, G., Xu, X., and . Key TJ, Silcocks PB, Davey GK, et al. Alder, R., Lookinland, S., Berry, J. View abstract. Garty BZ. View abstract. J Indian Soc.Pedod.Prev.Dent. 2006;136(3 Suppl):803S-805S. Pediatrics 2003;111(5 Pt 1):e574-e579. Contact Dermatitis 1997;37:70-7. Mohammed Abdul MI, Jiang X, Williams KM, et al. View abstract. View abstract. Int.J Dent.Hyg. Bradley R, Endres J, Hockenberry D, and et al. Bojs, G. and Svensson, A. Bleumink, E. and Nater, J. P. Contact dermatitis to garlic; crossreactivity between garlic, onion and tulip. Z Phytother 1984;5:938-942. Garlic as a possible risk for postoperative bleeding. Br J Clin Pract Suppl 1990;69:3-6. View abstract. Khodavandi, A., Alizadeh, F., Harmal, N. S., Sidik, S. M., Othman, F., Sekawi, Z., and Chong, P. P. Expression analysis of SIR2 and SAPs1-4 gene expression in Candida albicans treated with allicin compared to fluconazole. Arch Intern Med 1998;158:1189-94. Terms of Use. Modulation of lipid profile by fish oil and garlic combination. Guo, Y., Zhang, K., Wang, Q., Li, Z., Yin, Y., Xu, Q., Duan, W., and Li, C. Neuroprotective effects of diallyl trisulfide in SOD1-G93A transgenic mouse model of amyotrophic lateral sclerosis. Taking a specific garlic powder supplement (Allicor, INAT-Farma) twice daily for 24 months seems to reduce how much hardening of the arteries progresses. Lawson, L. D. Effect of garlic on serum lipids. View abstract. View abstract. Garlic might increase how quickly the liver breaks down some medications. JAMA 1998;279:1900-2. View abstract. Nutr.Cancer 2000;38(2):245-254. Delaney, T. A. and Donnelly, A. M. Garlic dermatitis. Lipids 1983;18:343-348. Huang, J., Frohlich, J., and Ignaszewski, A. P. The impact of dietary changes and dietary supplements on lipid profile. Z., and Li, B. Allitridum mimics effect of ischemic preconditioning by activation of protein kinase C. Acta Pharmacol.Sin. Phytother.Res. Am J Clin Nutr 1977;30(9):1380-1381. Lawson, L. D. Effect of garlic on serum lipids. Parastoui K, Ravanshad Sh Mostafavi H Setoudeh Maram E. Effects of garlic tablet on blood sugar, plasma lipids and blood pressure in type 2 diabetic patients with hyperlipidemia. J Natl Cancer Inst 1989;81:162-4. Biochim Biophys Acta 1994;1213(1):57-62. Bordia A. Knoblauch und koronare Herzkrankheit: Wirkungen einer dreijahrigen Behandlung min Knoblauchextrakt auf die Reinfarkt und Mortalitatsrate. Also, 300 mg of another specific garlic powder product (Garlex, Bosch Pharmaceuticals) taken twice daily for 12 weeks has been used. Planta Med 1992;58:8-13. Bagga, S., Thomas, B. S., and Bhat, M. Garlic burn as self-inflicted mucosal injury--a case report and review of the literature. 2012;8:CD007653. A., Nedosugova, L. V., Filatova, L. V., Balabolkin, M. I., Gorchakova, T. V., and Orekhov, A. N. Metabolic effects of time-released garlic powder tablets in type 2 diabetes mellitus: the results of double-blinded placebo-controlled study. View abstract. Garlic burns. View abstract. 1972;87(1):6-9. View abstract. Aktuelle Dermatol 1996;22:278-279. Pharmacology 2006;77:100-4. O'Gara EA, Hill DJ, Maslin DJ. Eur.J Appl.Physiol 2008;103(3):275-283. View abstract. Pediatr Res 1993;34:805-8. Int J Immunopharmacol. 1995;13(5):257-263. Fleischer S, Bayerl C, and Jung EG. Carden SM, Good WV, Carden PA, Good RM. Sato T, Miyata G. The Nutraceutical Benefit, Part IV: Garlic. View abstract. Campos, R., Amato, Neto, V, Castanho, R. E., Moreira, A. Acta Toxicol Ther 1990;11(4):365-372. View abstract. View abstract. View abstract. 2001;6(3):249-253. Arch Dermatol 1950;61:111. J Nutr 1983;113:1746-55. It is also used for fighting stress and fatigue. View abstract. Phytother.Res. View abstract. Campos, R., Amato, Neto, V, Castanho, R. E., Moreira, A. Fernandez-Vozmediano JM, Armario-Hita JC, Manrique-Plaza A. Allergic contact dermatitis from diallyl disulfide. 2009;32(3):191-203. A., and Pinto, P. L. [Treatment of ascaridiasis with garlic (Allium sativum)]. J R Coll Physicians Lond 1996;30:329-34. Nutr Cancer. 2009;139(1):106-112. View abstract. Liu, L. and Yeh, Y. Y. Inhibition of cholesterol biosynthesis by organosulfur compounds derived from garlic. Klin.Med (Mosk) 2007;85(3):25-28. Recent Pat Cardiovasc Drug Discov 2013;8(1):56-66. October 2000. Neurosurgery 1990;27(4):659. Botulism from chopped garlic: delayed recognition of a major outbreak. BMJ Case Rep 2014. 1. Efendy JL, Simmons DL, Campbell GR, Campbell JH. Br.J Clin Pract.Suppl 1990;69:20-23. Russell, J. E. Chinese complementary therapy for stress causing bilateral chemical burns to the feet. Effect of garlic powder tablets on blood lipids and blood pressure-a six month placebo controlled, double blind study. View abstract. A meta-analysis of the effect of garlic on blood pressure. Nature 10-14-1999;401(6754):629. Garlic might decrease how much saquinavir goes into the blood. Effects of garlic extract on platelet aggregation: a randomized placebo-controlled double-blind study. View abstract. View abstract. Pediatr.Emerg.Care 1987;3(4):258-260. Srivastava KC, Bordia A, and Verma SK. View abstract. Relation of oxidative biomarkers, vascular dysfunction, and progression of coronary artery calcium. A., Breckler, L., Hale, J., Lehmann, H., Franklin, P., Lyons, G., Ching, S. Y., Mori, T. A., Barden, A., and Prescott, S. L. Supplementation with vitamins C, E, beta-carotene and selenium has no effect on anti-oxidant status and immune responses in allergic adults: a randomized controlled trial. View abstract. Pedraza-Chaverri J, Tapia E, Medina-Campos ON, et al. 2-16-2011;1374:110-115. View abstract. Rapp, A., Grohmann, G., Oelzner, P., Uehleke, B., and Uhlemann, C. [Does garlic influence rheologic properties and blood flow in progressive systemic sclerosis?]. View abstract. 2012;19(1):26-30. View abstract. Prasad, S., Kalra, N., Srivastava, S., and Shukla, Y. J Am Acad.Nurse Pract. The antiatherosclerotic effect of Allium sativum. Fortschr.Med 12-20-1990;108(36):703-706. Dietary intake of garlic and other Allium vegetables and breast cancer risk in a prospective study of postmenopausal women. View abstract. Before taking garlic oil talk to your healthcare provider if you take any medications that are changed by the liver. Best Garlic Supplements. 2008;22(10):1372-1379. A historical perspective on garlic and cancer. Anti-diabetic effects of onion and garlic sulfoxide amino acids in rats. The effects of garlic preparation against human tumour cell proliferation. View abstract. View abstract. Bordia, A. J Nat Toxins. View abstract. WebMD does not provide medical advice, diagnosis or treatment. Pena, N., Auro, A., and Sumano, H. A comparative trial of garlic, its extract and ammonium-potassium tartrate as anthelmintics in carp. Jalloh MA, Gregory PJ, Hein D, et al. Ackermann RT, Mulrow CD, Ramirez G, et al. View abstract. Dorant E, van den Brandt PA, Goldbohm RA. 2007;66(5):508-514. View abstract. View abstract. Omurtag, G. Z., Guranlioglu, F. D., Sehirli, O., Arbak, S., Uslu, B., Gedik, N., and Sener, G. Protective effect of aqueous garlic extract against naphthalene-induced oxidative stress in mice. B., Varli, M., Devrim, E., Aras, S., and Durak, I. View abstract. Baruchin, A. M., Sagi, A., Yoffe, B., and Ronen, M. Garlic burns. Coppi, A., Cabinian, M., Mirelman, D., and Sinnis, P. Antimalarial activity of allicin, a biologically active compound from garlic cloves. Garlic products sold as health supplements may vary widely in amount of allicin, the active ingredient in garlic. Cancer Res 1994;54:6148-53. An unusual garlic burn occurring on an unexpected area. Atherosclerosis 1981;38:417-21. Colon cancer, rectal cancer. Baluchnejadmojarad, T., Roghani, M., Homayounfar, H., and Hosseini, M. Beneficial effect of aqueous garlic extract on the vascular reactivity of streptozotocin-diabetic rats. Adv Ther 2001;18:189-93. Atherosclerosis 1998;139:333-9. It seems to work best in people with diabetes, especially if it is taken for at least 3 months. Can J Physiol Pharmacol. Antimicrob.Agents Chemother 1988;32(12):1763-1768. J Hum Hypertens. Applying a gel containing 0.6% ajoene, a chemical in garlic, twice daily for one week seems to be as effective as antifungal medication for treating jock itch. Zeng T, Guo FF, Zhang CL, et al. Sci Am 1985;252(3):114-119. Effect of garlic (Allium sativum) on lipid peroxidation in experimental myocardial infarction in rats. Ahmadi N, Nabavi V, Hajsadeghi F, et al. Bordia, A., Verma, S. K., and Srivastava, K. C. Effect of garlic on platelet aggregation in humans: a study in healthy subjects and patients with coronary artery disease. 2009;139(1):106-112. View abstract. Banerjee, S. K., Dinda, A. K., Manchanda, S. C., and Maulik, S. K. Chronic garlic administration protects rat heart against oxidative stress induced by ischemic reperfusion injury. View abstract. View abstract. Shakeel, M., Trinidade, A., McCluney, N., and Clive, B. Complementary and alternative medicine in epistaxis: a point worth considering during the patient's history. Int J Mol.Med 2002;9(6):641-643. J Am Coll Nutr 2001;20(3):225-231. Studies on the anticandidal mode of action of Allium sativum (garlic). Razo-Rodriguez, A. C., Chirino, Y. I., Sanchez-Gonzalez, D. J., Martinez-Martinez, C. M., Cruz, C., and Pedraza-Chaverri, J. Garlic powder ameliorates cisplatin-induced nephrotoxicity and oxidative stress. Dietary intake of garlic and other Allium vegetables and breast cancer risk in a prospective study of postmenopausal women. But other early research suggests that taking garlic (Garlicin, Nature's Way) twice daily for 14 days does not improve symptoms. Dehghani F, Merat A, Panjehshahin MR, Handjani F. Healing effect of garlic extract on warts and corns. Taking garlic oil along with some medications that are changed by the liver can increase the effects and side effects of your medication. Int J Clin Pharmacol.Ther.Toxicol. 1980;93(2):123-126. Bordia A, Verma SK, Srivastava KC. Nutrition Research 1987;7:139-149. Comparative study of lifestyles of residents in high and low risk areas for gastric cancer in Jiangsu Province, China; with special reference to allium vegetables. View abstract. Garlic in cryptococcal meningitis: a preliminary report of 21 cases. Medications changed by the liver (Cytochrome P450 2E1 (CYP2E1) substrates) interacts with GARLIC. 2006;20(10):844-850. View abstract. View abstract. Pharmaceutical Biology (Netherlands) 2002;40:548-551. View abstract. Phytother.Res. A., Karabasova, IaA, Liutova, L. I., Povorinskaia, T. E., and Orekhov, A. N. [Use of allikor for the normalization of fibrinolysis and hemostasis in patients with chronic cerebrovascular diseases]. Kundakovic, T., Milenkovic, M., Zlatkovic, S., Nikolic, V., Nikolic, G., and Binic, I. Bagga, S., Thomas, B. S., and Bhat, M. Garlic burn as self-inflicted mucosal injury--a case report and review of the literature. Am J Clin Nutr 1981;34(10):2100-2103. Oral Health Prev.Dent. Pai, S. T. and Platt, M. W. Antifungal effects of Allium sativum (garlic) extract against the Aspergillus species involved in otomycosis. View abstract. Mukherjee, M., Das, A. S., Mitra, S., and Mitra, C. Prevention of bone loss by oil extract of garlic (Allium sativum Linn.) 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Taking garlic along with cyclosporine (Neoral, Sandimmune) might decrease the effectiveness of cyclosporine (Neoral, Sandimmune). 3-21-2012;104(6):488-492. 20 (Contract 290-97-0012 to the San Antonio Evidence-based Practice Center based at The University of Texas Health Science Center at San Antonio and the Veterans Evidence-based Research, Dissemination, and Implementation Center, a Veterans Affairs Health Services Research and Development Center of Excellence). Pinto, J. T., Qiao, C., Xing, J., Rivlin, R. S., Protomastro, M. L., Weissler, M. L., Tao, Y., Thaler, H., and Heston, W. D. Effects of garlic thioallyl derivatives on growth, glutathione concentration, and polyamine formation of human prostate carcinoma cells in culture. Planta Med 1989;55:114. Gaddoni G, Selvi M, Resta F, and et al. Zhang, Z. D., Li, Y., and Jiao, Z. K. [Effect of local application of allicinvia gastroscopy on cell proliferation and apoptosis of progressive gastric carcinoma]. Clin.Nutr. 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Allium sativum and Allium ursinum: chemistry, pharmacology and medicinal applications. Appl Environ.Microbiol 1996;62(11):4238-4242. Garlic is used in the vagina for yeast infections. J Natl.Cancer Inst. Some medications that are changed by the liver include acetaminophen, chlorzoxazone (Parafon Forte), ethanol, theophylline, and drugs used for anesthesia during surgery such as enflurane (Ethrane), halothane (Fluothane), isoflurane (Forane), and methoxyflurane (Penthrane). Orekhov AN, Sobenin IA, Korneev NV, et al. Nutrition 2000;16:236-9. Satitvipawee P, Rawdaree P, Indrabhakti S, et al. Ishikawa, H., Saeki, T., Otani, T., Suzuki, T., Shimozuma, K., Nishino, H., Fukuda, S., and Morimoto, K. Aged garlic extract prevents a decline of NK cell number and activity in patients with advanced cancer. Gastroenterology 2011;141(1):80-89. 1995;20(1):14-18. However, garlic is POSSIBLY UNSAFE when taken by mouth in large doses. But there is no reliable evidence that garlic is helpful for people who already have cancer. Can.J.Gastroenterol. Effect of garlic and fish-oil supplementation on serum lipid and lipoprotein concentrations in hypercholesterolemic men. View abstract. Ashraf, R., Aamir, K., Shaikh, A. R., and Ahmed, T. Effects of garlic on dyslipidemia in patients with type 2 diabetes mellitus. Oral Health Prev.Dent. Sigounas G, Hooker J, Anagnostou A, Steiner M. S-allylmercaptocysteine inhibits cell proliferation and reduces the viability of erythroleukemia, breast, and prostate cancer cell lines. Isaacsohn JL, Moser M, Stein EA, et al. Lipids Health Dis. Int J Mol.Med 2002;9(6):641-643. Cox MC, Low J, Lee J, et al. View abstract. Clin Investig 1993;71:383-6. View abstract. Tsai, Y., Cole, L. L., Davis, L. E., Lockwood, S. J., Simmons, V., and Wild, G. C. Antiviral properties of garlic: in vitro effects on influenza B, herpes simplex and coxsackie viruses. Dwivedi, C., Rohlfs, S., Jarvis, D., and Engineer, F. N. Chemoprevention of chemically induced skin tumor development by diallyl sulfide and diallyl disulfide. J Nutr. Meher S, Duley L. Garlic for preventing pre-eclampsia and its complications. The potential application of Allium sativum (garlic) for the treatment of bladder cancer. Taking garlic with other ingredients might have a small effect. View abstract. Xenobiotica 2002;32(12):1127-1138. Antibacterial activity of garlic powder against Escherichia coli O-157. , Sniecinski R. Garlic-induced surgical bleeding: how much saquinavir goes into the.... Venkatakrishnan L, Fabiani R. garlic consumption is inversely associated with prostate cancer a! Intestine ]: meta-analyses of colorectal cancer risk in men with coronary heart disease ascorbic acid and allicin evidence. For ongoing rashes no reliable evidence that garlic might cause damage to the intestine Res ;! 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